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This subject describes current technologies used to sequence genomes - the starting point for comparative analyses of genes and proteins. The field of informatics has evolved to analyse and interpret large amounts of data generated by the new biotechnologies. Advanced topics will include transcriptome technologies, genome evolution and sequence similarity analysis techniques to identify protein orthologues and paralogues. The subject will cover bioinformatic analysis of protein structure and motifs at the secondary and tertiary levels, and modelling studies aimed at drug design. This subject will explore the latest developments in bioinformatics and detail how systems biology is helping to model complex biological processes.
Intended learning outcomes
The objectives of this subject are to provide students with knowledge of:
- current concepts concerning the molecular basis of genome structure and gene expression;
- theoretical background to genome analysis strategies and technologies and an appreciation of their biotechnological applications;
- the significance and applications of human and other genome sequencing programs
- bioinformatic techniques and applications in the analysis of protein structure and function
Completion of this subject is expected to enhance the generic skills of students in:
- the ability to interpret scientific literature and interpret data from electronic databases.
- the ability to use information technology to acquire relevant knowledge for their understanding of the current status of the field and its relevance to society.
- the capacity to integrate knowledge across disciplines.
- the ability to comprehend a question, evaluate the relevant information and communicate an answer
- the capacity for independent critical thought, rational inquiry and self-directed learning and research.
Last updated: 9 February 2022