Bioinformatics is a multidisciplinary field that combines biology with quantitative methods to help understand biological processes, such as disease progression. This unit provides a broad-ranging study of this application of quantitative methods in biology. Content includes: biology basics; statistical genetics; web-based tools, data sources and data retrieval; the analysis of single and multiple DNA or protein sequences; Hidden Markov Models and their applications; evolutionary models; phylogenetic trees; transcriptomics (gene expression microarrays and RNA-seq); use of R in bioinformatics applications.
Intended learning outcomes
To provide an introduction to the field of bioinformatics from a statistical point of view. This will include an understanding of the basic concepts of molecular biology.
On completion students should have developed independent problem solving, facility with abstract reasoning, clarity of written expression, sound communication of technical concepts.