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Cell Signalling and Neurochemistry (BCMB30004)
Undergraduate level 3Points: 12.5Dual-Delivery (Parkville)
From 2023 most subjects will be taught on campus only with flexible options limited to a select number of postgraduate programs and individual subjects.
To learn more, visit COVID-19 course and subject delivery.
About this subject
- Overview
- Eligibility and requirements
- Assessment
- Dates and times
- Further information
- Timetable(opens in new window)
Contact information
Semester 2
Subject Co-ordinator
Professor Paul Gooley
Administrative Coordination
Overview
| Availability | Semester 2 - Dual-Delivery |
|---|---|
| Fees | Look up fees |
Aberrations in the structure and expression of hormones, growth factors, neurotransmitters and their receptors can give rise to diseases such as cancer and neurodegenerative diseases. To understand the molecular basis of these diseases, it is essential to know how hormones, growth factors and neurotransmitters are synthesised, and how their signals are recognised, amplified and transmitted by intracellular signalling pathways in the target cells.
Topics covered, to illustrate the importance of signalling in health and disease, include the structures of the major classes of signalling receptors, the mechanisms of intercellular and intracellular signal transduction, second messengers, examples of post-translational modifications such as protein phosphorylation-dephosphorylation, ubiquitination and S-nitrosylation and their impact on signalling, mechanisms of cell death and autophagy, and innate immune signalling.
Intended learning outcomes
On completion of the subject, the student should be able to:
- Describe the molecular basis of signal generation by cell surface receptors and intracellular receptors of hormones and neurotransmitters
- Describe the structural basis underpinning how cell signalling mediators recognise their substrates and catalyse post-translational modifications of their target proteins
- Devise experiments to investigate how dys-regulation of key cell signalling proteins contributes to diseases
- Perform computational analysis of the sequence and structure of signalling proteins
- Critically analyse of the current scientific literature on cell signalling and neuroscience research
Generic skills
On completion of this subject, students should have developed the following generic skills:
- the ability to interpret scientific literature and interpret data from electronic databases.
- the capacity to integrate knowledge across disciplines.
- the ability to comprehend a question, evaluate the relevant information and communicate an answer.
Last updated: 24 January 2023
Eligibility and requirements
Prerequisites
One of
| Code | Name | Teaching period | Credit Points |
|---|---|---|---|
| BCMB20002 | Biochemistry and Molecular Biology |
Semester 2 (Dual-Delivery - Parkville)
Semester 1 (Online)
|
12.5 |
| BIOM20001 | Molecular and Cellular Biomedicine | Semester 1 (Dual-Delivery - Parkville) |
25 |
Other combinations that provide similar background will be considered by the coordinator.
Corequisites
None
Non-allowed subjects
None
Inherent requirements (core participation requirements)
The University of Melbourne is committed to providing students with reasonable adjustments to assessment and participation under the Disability Standards for Education (2005), and the Assessment and Results Policy (MPF1326). Students are expected to meet the core participation requirements for their course. These can be viewed under Entry and Participation Requirements for the course outlines in the Handbook.
Further details on how to seek academic adjustments can be found on the Student Equity and Disability Support website: http://services.unimelb.edu.au/student-equity/home
Last updated: 24 January 2023
Assessment
| Description | Timing | Percentage |
|---|---|---|
5-10 written assessments totalling approx. 1600 words and prepared figures
| Throughout the semester | 35% |
Mid Semester Test 1
| Around week 5 | 10% |
Mid Semester Test 2
| Around week 10 | 10% |
Exam
| During the examination period | 45% |
Attendance at 70% of workshops Hurdle requirement: Attendance at 70% of workshops i.e. 10-11 x 2 hour workshops | Throughout the semester | N/A |
Last updated: 24 January 2023
Dates & times
- Semester 2
Coordinator Paul Gooley Mode of delivery Dual-Delivery (Parkville) Contact hours 2 hours of workshops per week Total time commitment 170 hours Teaching period 25 July 2022 to 23 October 2022 Last self-enrol date 5 August 2022 Census date 31 August 2022 Last date to withdraw without fail 23 September 2022 Assessment period ends 18 November 2022 Semester 2 contact information
Subject Co-ordinator
Professor Paul Gooley
Administrative Coordination
Time commitment details
170 hours
Last updated: 24 January 2023
Further information
- Texts
Prescribed texts
There are no specifically prescribed or recommended texts for this subject.
- Subject notes
Students enrolled in the BSc (pre-2008 BSc), BASc or a combined BSc course will receive science credit for the completion of this subject.
Students undertaking this subject will be expected to regularly access an Internet-enabled computer.
- Related Handbook entries
This subject contributes to the following:
Type Name Major Biochemistry and Molecular Biology Informal specialisation Science Discipline subjects - new generation B-SCI Major Neuroscience Major Neuroscience Major Biochemistry and Molecular Biology - Available through the Community Access Program
About the Community Access Program (CAP)
This subject is available through the Community Access Program (also called Single Subject Studies) which allows you to enrol in single subjects offered by the University of Melbourne, without the commitment required to complete a whole degree.
Entry requirements including prerequisites may apply. Please refer to the CAP applications page for further information.
- Available to Study Abroad and/or Study Exchange Students
This subject is available to students studying at the University from eligible overseas institutions on exchange and study abroad. Students are required to satisfy any listed requirements, such as pre- and co-requisites, for enrolment in the subject.
Last updated: 24 January 2023