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Laboratory Models of Human Disease (BMSC90021)
Graduate courseworkPoints: 12.5On Campus (Parkville)
About this subject
Contact information
Semester 1
Subject Coordinators
Gary Hime
g.hime@unimelb.edu.au
Charlotte Clark
charlotte.clark@unimelb.edu.au
Administrative Coordination
Overview
Availability | Semester 1 |
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Fees | Look up fees |
Personalized medicine is the end goal of advances in genomics. Many patients are now able to have their genome sequenced and many, many new human sequence variants are being discovered on a weekly basis. How can these data be analysed to benefit the patient? How can we interpret genomic data to determine if a sequence variant is likely to be pathological or be causative for a specific disease phenotype. This subject will provide students with experience of a pipeline that can be used to analyse genomic variants and a framework for decision-making about the types of laboratory studies that can be utilized to gain further information about a gene and related sequence variants.
Intended learning outcomes
On completion of this subject, students should be able to:
- Analyse how genetic variants are identified in the clinic.
- Synthesise ethical and patient-centred issues associated with genomic sequencing and evaluate strategies to address these.
- Apply relevant technologies to investigate pathological genetic variation and interpret the data obtained from these analyses.
- Design a workflow utilising a range of experimental techniques to analyse the function of genomic variants.
- Evaluate various models available for analysis of gene and protein function.
Generic skills
- The ability to work collaboratively and constructively in a multidisciplinary and multicultural team environment
- Time management, self-regulation, project management and problem-solving skills
- The ability to collect, analyse, interpret and critically evaluate authentic scientific data
- The ability to communicate with varied audiences and stakeholders using appropriate written, oral and visual communication skills
Last updated: 8 November 2024