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Current Challenges in Metabolic Diseases (BMSC90022)
Graduate courseworkPoints: 12.5On Campus (Parkville)
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Semester 1
Overview
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In health, metabolic function involves the integrated operation of all body systems to ensure that metabolic fuel supply is attuned to the fuel usage requirements of every organ, tissue and cell. In metabolic disease, the integrated operations of the primary fuel supply regulator (liver) and the major energy consumer tissues (especially heart and skeletal muscle) are disrupted. Metabolic disruption is the basis of major global health burdens - including diabetes, obesity, heart failure, and cancer. In this subject Researchers will lead discussions to introduce students to the paradigms of metabolic research, examining how questions can be formulated to drive knowledge forward and how different models and technologies can be used to generate translational outcomes.
Intended learning outcomes
On completion of this subject, students should be able to:
- Explain how specific metabolic diseases develop and identify what tissues and cellular mechanisms are involved.
- Analyse various pre-clinical model systems used for discovery and therapeutic advancement.
- Evaluate the regulatory requirements involved in the use of pre-clinical models for both discovery research and therapeutic development.
- Design and perform relevant experiments in metabolism research using in vitro and in vivo model systems and interpret and analyse the data obtained.
Generic skills
- The ability to work collaboratively and constructively in a multidisciplinary and multicultural team environment.
- Time management, self-regulation, project management and problem-solving skills.
- The ability to collect, analyse, interpret and critically evaluate authentic scientific data.
- The ability to communicate with varied audiences and stakeholders using appropriate written, oral and visual communication skills.
Last updated: 8 November 2024