Experimental Developmental Biology (CEDB30003)

In this subject, students will learn about the process of developmental biology, from fertilisation of an egg by a sperm to the emergence of a living animal. Students will explore how developmental processes are integral to our understanding of human genetic disease and tissue bioengineering. Subject learning materials provide students with in-depth knowledge of the molecular, genetic and cellular events that regulate the development of specialised cells, tissues, and organs. In particular, students will learn about the processes that regulate embryonic induction, tissue interactions and pattern formation. Weekly workshops allow students to explore this information in more detail and discuss key topics with peers and teaching staff. In a series of guided laboratory practicals, students will get hands-on experience in visualising and manipulating developing embryos, providing an authentic and engaging introduction to real scientific research. This subject is suitable for students interested in cellular and developmental biology, and for any student with a relevant background who is fascinated by developmental biology.

Intended learning outcomes

On completion of this subject, students should be able to:

• Describe the processes by which a single cell can generate an entire multi-cellular organism.
• Explain the molecular, genetic and cellular mechanisms by which cells can build tissues, and organs during embryonic development, by pattern formation, morphological changes, and differentiation into specialised types.
• Explain how model organisms are used to address fundamental principles of development due to the conservation of genes and processes across the diversity of life.
• Describe current genetic, molecular and cellular techniques, including genome editing, being used to investigate developmental biology.
• Demonstrate proficiency in observational and technical laboratory and microscopy skills to collect, analyse, interpret and present experimental data.
• Work effectively in diverse groups to investigate and communicate concepts in cell and developmental biology.
• Critically analyse scientific literature in developmental biology to explain the significance of seminal papers in advancing the field.
• Apply developmental principles to related fields such as regeneration, cancer, and stem-cell therapy, and appreciate the ethical implications of emerging techniques.

Generic skills