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Systems and Synthetic Biology (BMEN90027)
Graduate courseworkPoints: 12.5Not available in 2024
Overview
Fees | Look up fees |
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AIMS:
This subject introduces mathematical and computational modelling, simulation and analysis of biological systems. The emphasis is on developing models, with examples, using MATLAB.
INDICATIVE CONTENT:
Topics include:
Modelling biochemical reactions. Law of mass action. Enzymes and regulation of enzyme reactions. Thermodynamics of reversible biochemical reactions. Cellular homeostasis. Application of ordinary differential equations to these problems.
Modelling large reaction networks. Flux balance analysis and constraint-based methods. Genome-scale models. Regulation of gene expression. Gene regulatory networks in systems and synthetic biology. Network inference and statistical modelling of –omic data. Knowledge-based modelling in systems biology.
Intended learning outcomes
On completion of this subject the student is expected to:
- Evaluate the role for mathematical and computational modelling of biological systems;
- Employ the law of mass action to develop ODE models for biochemical reactions;
- Develop and analyse models for enzyme catalysed reactions in cellular bioengineering and synthetic biology;
- Demonstrate the use of ODE and PDE models in molecular and cellular physiology;
- Describe the premise of systems and synthetic biology;
- Develop and analyse large-scale network models for biosystems and synthetic biology;
- Explain the role of knowledge-based modelling in systems biology;
- Evaluate and employ the measurement technologies and sources of data underlying systems and synthetic biology, including data repositories and different modelling approaches.
Generic skills
On completion of this subject students should have developed the following generic skills:
- Ability to apply knowledge of science and engineering fundamentals.
- Ability to communicate effectively, with the engineering team and with the community at large.
- Capacity for lifelong learning and professional development.
- Profound respect for truth and intellectual integrity, and for the ethics of scholarship.
Last updated: 31 January 2024
Eligibility and requirements
Prerequisites
Code | Name | Teaching period | Credit Points |
---|---|---|---|
MAST20029 | Engineering Mathematics |
Summer Term (On Campus - Parkville)
Semester 1 (On Campus - Parkville)
Semester 2 (On Campus - Parkville)
|
12.5 |
OR
One of
Code | Name | Teaching period | Credit Points |
---|---|---|---|
MAST20009 | Vector Calculus |
Semester 2 (On Campus - Parkville)
Semester 1 (On Campus - Parkville)
|
12.5 |
MAST20032 | Vector Calculus: Advanced | Semester 1 (On Campus - Parkville) |
12.5 |
AND
Code | Name | Teaching period | Credit Points |
---|---|---|---|
MAST20030 | Differential Equations | Semester 2 (On Campus - Parkville) |
12.5 |
OR
Equivalent Mathematics subject
Corequisites
None
Non-allowed subjects
None
Inherent requirements (core participation requirements)
The University of Melbourne is committed to providing students with reasonable adjustments to assessment and participation under the Disability Standards for Education (2005), and the Assessment and Results Policy (MPF1326). Students are expected to meet the core participation requirements for their course. These can be viewed under Entry and Participation Requirements for the course outlines in the Handbook.
Further details on how to seek academic adjustments can be found on the Student Equity and Disability Support website: http://services.unimelb.edu.au/student-equity/home
Last updated: 31 January 2024
Assessment
Description | Timing | Percentage |
---|---|---|
Participation in up to six workshops in Weeks 2 to 12, of which 4 are assessed with a written assignment of approximately 500 words, requiring 13-15 hours of work including preparation (10% each).
| From Week 2 to Week 12 | 40% |
One mid-semester test
| Week 7 | 10% |
One written examination
| End of semester | 50% |
Additional details
Intended Learning Outcomes (ILOs) 1 to 8 are assessed in the final written examination, assignments and workshop reports. ILOs 1 to 4 are also assessed in the mid-semester test.
Last updated: 31 January 2024
Dates & times
Not available in 2024
Time commitment details
200 hours
What do these dates mean
Visit this webpage to find out about these key dates, including how they impact on:
- Your tuition fees, academic transcript and statements.
- And for Commonwealth Supported students, your:
- Student Learning Entitlement. This applies to all students enrolled in a Commonwealth Supported Place (CSP).
Subjects withdrawn after the census date (including up to the ‘last day to withdraw without fail’) count toward the Student Learning Entitlement.
Last updated: 31 January 2024
Further information
- Texts
Prescribed texts
- Related Handbook entries
This subject contributes to the following:
Type Name Course Master of Biomedical Engineering Course Master of Science (Mathematics and Statistics) Specialisation (formal) Biomedical Specialisation (formal) Biomedical with Business Specialisation (formal) Business - Available through the Community Access Program
About the Community Access Program (CAP)
This subject is available through the Community Access Program (also called Single Subject Studies) which allows you to enrol in single subjects offered by the University of Melbourne, without the commitment required to complete a whole degree.
Entry requirements including prerequisites may apply. Please refer to the CAP applications page for further information.
Additional information for this subject
Subject coordinator approval required
- Available to Study Abroad and/or Study Exchange Students
This subject is available to students studying at the University from eligible overseas institutions on exchange and study abroad. Students are required to satisfy any listed requirements, such as pre- and co-requisites, for enrolment in the subject.
Last updated: 31 January 2024