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Design of Randomised Controlled Trials (POPH90119)
Graduate courseworkPoints: 12.5Online
About this subject
- Overview
- Eligibility and requirements
- Assessment
- Dates and times
- Further information
- Timetable (login required)(opens in new window)
Contact information
Semester 2
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: https://study.unimelb.edu.au/
Overview
| Availability | Semester 2 - Online |
|---|---|
| Fees | Look up fees |
Topics include: ethical considerations; principles and methods of randomisation in controlled trials; treatment allocation, blocking, stratification and allocation concealment; parallel, factorial and crossover designs including n-of-1 studies; practical issues in sample size determination; intention-to-treat principle; phase I dose finding studies; phase II safety and efficacy studies; interim analysis and early stopping ; multiple outcomes/endpoints, including surrogate outcomes, multiple tests and subgroup analyses, including adjustment of significance levels and P-values; missing data; reporting trial results and use of the CONSORT statement.
Intended learning outcomes
On completion of this subject, students should be able to:
- To enable students to understand and apply the principles of design and analysis of experiments, with a particular focus on randomised controlled trials (RCTs), to a level where they are able to contribute effectively as a statistician to the planning, conduct and reporting of a standard RCT.
Generic skills
Independent problem solving, critical appraisal of research literature, clarity of written expression, sound communication of technical concepts
Last updated: 12 February 2024