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  3. Soft Tissue and Cellular Biomechanics

Soft Tissue and Cellular Biomechanics (BMEN90029)

Graduate courseworkPoints: 12.5On Campus (Parkville)

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Overview

Availability
Semester 1
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AIMS

This subject aims to develop students’ knowledge and capabilities in experimental and computational biomechanics of cells and soft-tissues. Students will apply fundamental mathematical theory of nonlinear continuum mechanics and computational approaches to solve stress-equilibrium equations. Students will learn fundamentals in cell signalling and how cell- and sub-cellular-level processes affect cell and tissue mechanical properties. These concepts will be put to practice in project-based and examination assessments.

INDICATIVE CONTENT

  • Nonlinear continuum mechanics theory
  • Computational techniques for solving nonlinear mechanics problems
  • Soft-tissue mechanical properties
  • Cytoskeletal networks and mechanics
  • Signalling pathtways and systems-biology related to mechanics of cells and tissues

 

Intended learning outcomes

Intended Learning Outcomes (ILOs)


On successful completion of this subject, students should be able to:



  • Describe the fundamental mathematical principles behind nonlinear continuum mechanics
  • Describe and construct biochemical models of cell signalling pathways that affect cell and tissue mechanics
  • Construct computational models of the mechanics of soft-tissues and cells
  • Describe how the mechanical behaviour of cells and tissues in the body are regulated by chemical and mechanical signals
  • Construct multi-scale models of mechanics and signalling in cells and tissues
  • Demonstrate skills in communicating results from engineering research in written form.

Generic skills

On completion of this subject, students should have developed the following skills:

  • The ability to undertake problem identification, formulation and solution
  • Capacity for independent critical thought, rational inquiry and self-directed learning
  • Profound respect for truth and intellectual integrity, and for the ethics of scholarship
  • An ability to apply knowledge of basic science and engineering fundamentals

Last updated: 3 November 2022