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This subject introduces the chemical logic of cellular processes, and the chemical methods used to probe and perturb them. Coverage includes: the major classes of biomolecules and their biosynthesis with a focus on molecular structure; biological catalysis (enzymes, enzyme kinetics and the roles of trace metals and co-factors); and chemical methods for studying interactions and deconvoluting biological systems.
Also covered are chemical techniques for qualitative and quantitative analysis of cellular processes and biomolecular interactions; imaging techniques for non-invasive analysis; analytical techniques and equipment for biomolecular studies; and common molecular tools.
A key aspect of this subject will be the use of case studies to explore how chemical approaches can be applied to illuminate the molecular features of biological systems. This will be covered in a small-group learning mode and involve both a written report and oral presentation.
Intended learning outcomes
On completion of this subject students should be able to:
- Critically analyse problems at the interface of chemistry and biology
- Explain the molecular basis of a range of biological processes
- Interpret biological data by applying diverse chemical principles
- Explain the principles of the key analytical methods used in chemical biology
This subject will provide students with opportunities to develop the following generic skills:
- The ability to comprehend complex concepts and effectively communicate this understanding to scientists within and outside of the chemistry discipline
- The ability to critically analyse and solve abstract technical problems using data acquired through a range of technologies
- The ability to assimilate and apply the learnt concepts to a broad range of scientific problems within a scientific paradigm
- The ability to use conceptual models to rationalise observations
- Project planning and delivery skills including: planning and time-management; report-writing and oral presentation; working in collaborative groups
- Work effectively in small teams
Last updated: 16 June 2020