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Design of Randomised Controlled Trials (POPH90119)
Graduate courseworkPoints: 12.5Online
For information about the University’s phased return to campus and in-person activity in Winter and Semester 2, please refer to the on-campus subjects page.
About this subject
- Overview
- Eligibility and requirements
- Assessment
- Dates and times
- Further information
- Timetable(opens in new window)
Contact information
Semester 2
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: MSPGH Website
- Email: Enquiry Form
Please refer to the LMS for up-to-date subject information, including assessment and participation requirements, for subjects being offered in 2020.
Overview
Availability | Semester 2 - Online |
---|---|
Fees | Look up fees |
Topics include: ethical considerations; principles and methods of randomisation in controlled trials; treatment allocation, blocking, stratification and allocation concealment; parallel, factorial and crossover designs including n-of-1 studies; practical issues in sample size determination; intention-to-treat principle; phase I dose finding studies; phase II safety and efficacy studies; interim analysis and early stopping ; multiple outcomes/endpoints, including surrogate outcomes, multiple tests and subgroup analyses, including adjustment of significance levels and P-values; missing data; reporting trial results and use of the CONSORT statement.
Intended learning outcomes
To enable students to understand and apply the principles of design and analysis of experiments, with a particular focus on randomised controlled trials (RCTs), to a level where they are able to contribute effectively as a statistician to the planning, conduct and reporting of a standard RCT.
Generic skills
Independent problem solving, critical appraisal of research literature, clarity of written expression, sound communication of technical concepts
Last updated: 3 November 2022
Eligibility and requirements
Prerequisites
POPH90014 Epidemiology 1 OR POPH90016 Epidemiology
Corequisites
None
Non-allowed subjects
None
Inherent requirements (core participation requirements)
The University of Melbourne is committed to providing students with reasonable adjustments to assessment and participation under the Disability Standards for Education (2005), and the Assessment and Results Policy (MPF1326). Students are expected to meet the core participation requirements for their course. These can be viewed under Entry and Participation Requirements for the course outlines in the Handbook.
Further details on how to seek academic adjustments can be found on the Student Equity and Disability Support website: http://services.unimelb.edu.au/student-equity/home
Last updated: 3 November 2022
Assessment
Due to the impact of COVID-19, assessment may differ from that published in the Handbook. Students are reminded to check the subject assessment requirements published in the subject outline on the LMS
Description | Timing | Percentage |
---|---|---|
Three written assignments submitted during the semester; Two worth 30% each (approx 10 hours work each) and one worth 40% (approx 12 hours work).
| During the teaching period | 100% |
Last updated: 3 November 2022
Dates & times
- Semester 2 - Online
Principal coordinator John Carlin Mode of delivery Online Contact hours None Total time commitment 170 hours Teaching period 3 August 2020 to 1 November 2020 Last self-enrol date 14 August 2020 Census date 21 September 2020 Last date to withdraw without fail 16 October 2020 Assessment period ends 27 November 2020 Semester 2 contact information
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: MSPGH Website
- Email: Enquiry Form
Time commitment details
170 hours
Last updated: 3 November 2022
Further information
- Texts
Prescribed texts
Matthews JNS. Introduction to Randomized Controlled Clinical Trials. 2nd edition. Chapman and Hall / CRC Press 2006.
Resources Provided to Students: Printed course notes and assignment material by mail, email, and online interaction facilities. - Subject notes
This subject is delivered online via our partners in the Biostatistics Collaboration of Australia (www.bca.edu.au). It is not generally available in the Master of Public Health nor in any program outside the MSPGH.
- Related Handbook entries
This subject contributes to the following:
Type Name Course Graduate Diploma in Biostatistics Course Master of Biostatistics - Links to additional information
- Available to Study Abroad and/or Study Exchange Students
This subject is available to students studying at the University from eligible overseas institutions on exchange and study abroad. Students are required to satisfy any listed requirements, such as pre- and co-requisites, for enrolment in the subject.
Last updated: 3 November 2022