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Design of Randomised Controlled Trials (POPH90119)
Graduate courseworkPoints: 12.5Online
From 2023 most subjects will be taught on campus only with flexible options limited to a select number of postgraduate programs and individual subjects.
To learn more, visit COVID-19 course and subject delivery.
About this subject
- Overview
- Eligibility and requirements
- Assessment
- Dates and times
- Further information
- Timetable(opens in new window)
Contact information
Semester 2
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: MSPGH Website
- Email: Enquiry Form
Overview
Availability | Semester 2 - Online |
---|---|
Fees | Look up fees |
Topics include: ethical considerations; principles and methods of randomisation in controlled trials; treatment allocation, blocking, stratification and allocation concealment; parallel, factorial and crossover designs including n-of-1 studies; practical issues in sample size determination; intention-to-treat principle; phase I dose finding studies; phase II safety and efficacy studies; interim analysis and early stopping ; multiple outcomes/endpoints, including surrogate outcomes, multiple tests and subgroup analyses, including adjustment of significance levels and P-values; missing data; reporting trial results and use of the CONSORT statement.
Intended learning outcomes
On completion of this subject, students should be able to:
- To enable students to understand and apply the principles of design and analysis of experiments, with a particular focus on randomised controlled trials (RCTs), to a level where they are able to contribute effectively as a statistician to the planning, conduct and reporting of a standard RCT.
Generic skills
Independent problem solving, critical appraisal of research literature, clarity of written expression, sound communication of technical concepts
Last updated: 31 January 2024
Eligibility and requirements
Prerequisites
Code | Name | Teaching period | Credit Points |
---|---|---|---|
POPH90014 | Epidemiology 1 | Semester 1 (Online) |
12.5 |
Corequisites
None
Non-allowed subjects
None
Inherent requirements (core participation requirements)
The University of Melbourne is committed to providing students with reasonable adjustments to assessment and participation under the Disability Standards for Education (2005), and the Assessment and Results Policy (MPF1326). Students are expected to meet the core participation requirements for their course. These can be viewed under Entry and Participation Requirements for the course outlines in the Handbook.
Further details on how to seek academic adjustments can be found on the Student Equity and Disability Support website: http://services.unimelb.edu.au/student-equity/home
Last updated: 31 January 2024
Assessment
Description | Timing | Percentage |
---|---|---|
Three written assignments submitted during the semester; Two worth 30% each (approx 10 hours work each) and one worth 40% (approx 12 hours work).
| During the teaching period | 100% |
Last updated: 31 January 2024
Dates & times
- Semester 2 - Online
Principal coordinator John Carlin Mode of delivery Online Contact hours None Total time commitment 170 hours Teaching period 25 July 2022 to 23 October 2022 Last self-enrol date 5 August 2022 Census date 31 August 2022 Last date to withdraw without fail 23 September 2022 Assessment period ends 18 November 2022 Semester 2 contact information
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: MSPGH Website
- Email: Enquiry Form
Time commitment details
170 hours
Last updated: 31 January 2024
Further information
- Texts
Prescribed texts
Matthews JNS. Introduction to Randomized Controlled Clinical Trials. 2nd edition. Chapman and Hall / CRC Press 2006.
Resources Provided to Students: Printed course notes and assignment material by mail, email, and online interaction facilities. - Subject notes
This subject is delivered online via our partners in the Biostatistics Collaboration of Australia (www.bca.edu.au). It is not generally available in the Master of Public Health nor in any program outside the MSPGH.
- Related Handbook entries
This subject contributes to the following:
Type Name Course Master of Biostatistics Course Graduate Diploma in Biostatistics - Links to additional information
- Available to Study Abroad and/or Study Exchange Students
This subject is available to students studying at the University from eligible overseas institutions on exchange and study abroad. Students are required to satisfy any listed requirements, such as pre- and co-requisites, for enrolment in the subject.
Last updated: 31 January 2024