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Design of Randomised Controlled Trials (POPH90119)
Graduate courseworkPoints: 12.5Online
About this subject
- Overview
- Eligibility and requirements
- Assessment
- Dates and times
- Further information
- Timetable (login required)(opens in new window)
Contact information
Semester 2
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: https://study.unimelb.edu.au/
Overview
| Availability | Semester 2 - Online |
|---|---|
| Fees | Look up fees |
Topics include: ethical considerations; principles and methods of randomisation in controlled trials; treatment allocation, blocking, stratification and allocation concealment; parallel, factorial and crossover designs including n-of-1 studies; practical issues in sample size determination; intention-to-treat principle; phase I dose finding studies; phase II safety and efficacy studies; interim analysis and early stopping ; multiple outcomes/endpoints, including surrogate outcomes, multiple tests and subgroup analyses, including adjustment of significance levels and P-values; missing data; reporting trial results and use of the CONSORT statement.
Intended learning outcomes
On completion of this subject, students should be able to:
- To enable students to understand and apply the principles of design and analysis of experiments, with a particular focus on randomised controlled trials (RCTs), to a level where they are able to contribute effectively as a statistician to the planning, conduct and reporting of a standard RCT.
Generic skills
Independent problem solving, critical appraisal of research literature, clarity of written expression, sound communication of technical concepts
Last updated: 12 February 2024
Eligibility and requirements
Prerequisites
| Code | Name | Teaching period | Credit Points |
|---|---|---|---|
| POPH90014 | Epidemiology 1 |
Semester 2 (Dual-Delivery - Parkville)
Semester 1 (Dual-Delivery - Parkville)
|
12.5 |
Corequisites
None
Non-allowed subjects
None
Inherent requirements (core participation requirements)
The University of Melbourne is committed to providing students with reasonable adjustments to assessment and participation under the Disability Standards for Education (2005), and the Assessment and Results Policy (MPF1326). Students are expected to meet the core participation requirements for their course. These can be viewed under Entry and Participation Requirements for the course outlines in the Handbook.
Further details on how to seek academic adjustments can be found on the Student Equity and Disability Support website: http://services.unimelb.edu.au/student-equity/home
Last updated: 12 February 2024
Assessment
| Description | Timing | Percentage |
|---|---|---|
Three written assignments submitted during the semester; Two worth 30% each (approx 10 hours work each) and one worth 40% (approx 12 hours work).
| During the teaching period | 100% |
Last updated: 12 February 2024
Dates & times
- Semester 2 - Online
Principal coordinator John Carlin Mode of delivery Online Contact hours None Total time commitment 170 hours Teaching period 22 July 2024 to 20 October 2024 Last self-enrol date 2 August 2024 Census date 2 September 2024 Last date to withdraw without fail 20 September 2024 Assessment period ends 15 November 2024 Semester 2 contact information
Melbourne School of Population and Global Health
OR
Currently enrolled students:
- General information: https://ask.unimelb.edu.au
- Email: Contact Stop 1
Future Students:
- Further Information: https://study.unimelb.edu.au/
Time commitment details
170 hours
What do these dates mean
Visit this webpage to find out about these key dates, including how they impact on:
- Your tuition fees, academic transcript and statements.
- And for Commonwealth Supported students, your:
- Student Learning Entitlement. This applies to all students enrolled in a Commonwealth Supported Place (CSP).
Subjects withdrawn after the census date (including up to the ‘last day to withdraw without fail’) count toward the Student Learning Entitlement.
Last updated: 12 February 2024
Further information
- Texts
Prescribed texts
Friedman L, Furberg C, DeMets D, Reboussin D, Grange C. Fundamentals of clinical trials, 5th edition, Springer 2015
For details, including ISBN, see the BCA Textbook Guide
Resources Provided to Students: Printed course notes and assignment material by mail, email, and online interaction facilities. - Subject notes
This subject is delivered online via our partners in the Biostatistics Collaboration of Australia (www.bca.edu.au). It is not generally available in the Master of Public Health nor in any program outside the MSPGH.
- Related Handbook entries
This subject contributes to the following:
Type Name Course Graduate Diploma in Biostatistics Course Master of Biostatistics - Links to additional information
Last updated: 12 February 2024