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Advanced NMR Spectroscopy (CHEM90065)

Graduate courseworkPoints: 6.25On Campus (Parkville)

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Overview

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This subject will discuss the theory of nuclear magnetic resonance (NMR) spectroscopy, relevant experimental techniques and its application in molecular structure determination. The theory of pulse Fourier Transform NMR will be presented along with the methods of spectral processing. Key aspects of proton chemical shift, spin-spin coupling and coupling constants will be discussed. 13C and heteronuclear NMR spectroscopy as well as the theory and application of advanced 2D techniques will also be detailed. A combination of 1D and 2D methods will be applied to determine the structure of complex molecules.

Intended learning outcomes

On the completion of this subject, students should be able to: 

  • Demonstrate an understanding of the fundamental aspects of NMR spectroscopy;
  • Explain the various experimental NMR techniques for the measurement of different types of NMR spectra;
  • Interpret and assign one- and two-dimensional NMR spectra and use the information to determine the structure of complex molecules
  • Demonstrate an increased knowledge and understanding of chemical science;
  • Use investigative skills, critical thought and the ability to evaluate information and to analyse experimental data

Generic skills

On completion of this subject, students should have:

  • Advanced problem-solving and critical thinking skills
  • An ability to evaluate the professional literature
  • An understanding of the changing knowledge base
  • A capacity to apply concepts developed in one area to a different context
  • The ability to use conceptual models to rationalize experimental observations

Last updated: 31 January 2024