Biomolecular Structure Determination (SCIE90026)
Graduate courseworkPoints: 12.5On Campus (Parkville)
Overview
| Availability(Quotas apply) | Semester 2 |
|---|---|
| Fees | Look up fees |
This subject provides an in-depth look into the methods, algorithms and techniques behind biomolecular structure determination. In particular, students will be exposed to prominent techniques in the field for example: X-ray Crystallography, Nuclear Magnetic Resonance (NMR) and cryogenic-Electron Microscopy (cryo-EM). As part of a general introduction into measurement techniques students will visit state-of-the-art NMR, cryo-EM and X-ray facilities at the Bio21 Institute and the Australian Synchrotron. Using industry standard software packages, students will learn to input and handle data to reconstruct biomolecular structure and dynamics across the range of techniques. The computer based laboratories will be overseen by practitioners in the field. This multi-disciplinary subject is co-taught by staff in the School of Physics, Chemistry and Biomedical sciences. There is particular emphasis on integration of these disciplines with students receiving both theoretical and practical knowledge of fundamental and frontier research and development in biomolecular structure determination.
Intended learning outcomes
On completion of this subject the student should be able to:
- Explain the measurement principles used to perform bio-molecular structure determination.
- Demonstrate high level computer based skills that can be used to study a range of biomolecular structural problems in biology.
- Compare and contrast the strengths and weakness of each technique and explain how they can be applied to advance how these techniques may be applied both in advanced scientific research and biotechnology development.
- Understand and articulate advances in biomolecular imaging and structure determination.
Generic skills
- Ability to undertake problem identification, formulation and solution;
- Ability to utilise computer based systems to solve complex problems;
- Ability to manage information and documentation;
- Capacity for creativity and innovation;
- Ability to communicate effectively within an interdisciplinary environment.
Last updated: 8 November 2024
Eligibility and requirements
Prerequisites
None
Corequisites
None
Non-allowed subjects
None
Inherent requirements (core participation requirements)
This subject requires all students to possess:
- the ability to comprehend complex science and technology related information;
- the ability to clearly and independently communicate a knowledge and application of science, and technology principles and practices during assessment tasks;
- the ability to actively and safely contribute in laboratory, and excursion activities.
Students must possess behavioural and social attributes that enable them to participate in a complex learning environment. Students are required to take responsibility for their own participation and learning. They also contribute to the learning of other students in collaborative learning environments, demonstrating interpersonal skills and an understanding of the needs of other students. Assessment may include the outcomes of tasks completed in collaboration with other students. Students who feel their disability will impact on meeting this requirement are encouraged to discuss this matter with the relevant Subject Coordinator and Student Equity and Disability Support website: http://services.unimelb.edu.au/student-equity/home
Last updated: 8 November 2024
Assessment
Semester 2
| Description | Timing | Percentage |
|---|---|---|
Computer programming assignment 1 (1000-1500 words), contributing 25%. Addressing Intended Learning Outcomes 2&3.
| Week 4 | 25% |
Computer programming assignment 2 (1000-1500 words), contributing 25%. Addressing Intended Learning Outcomes 2&3.
| Week 8 | 25% |
Computer programming assignment 3 (1000-1500 words), contributing 25%. Addressing Intended Learning Outcomes 2&3.
| Week 12 | 25% |
Exam - End of Semester (1 hour), contributing 25%. Addressing Intended Learning Outcomes 1&4.
| During the examination period | 25% |
Additional details
This Dual-Delivery subject has On Campus assessment components.
Last updated: 8 November 2024
Quotas apply to this subject
Dates & times
- Semester 2
Coordinator Ivanhoe Leung Mode of delivery On Campus (Parkville) Contact hours 9 x 1 hr lectures - Total 9 hours 3 x 3 hour field trips - Total 9 hours 18 x 2 hr computer based practical/tutorial - Total 36 hours Total contact hours - 54 hrs Total time commitment 160 hours Teaching period 22 July 2024 to 20 October 2024 Last self-enrol date 2 August 2024 Census date 2 September 2024 Last date to withdraw without fail 20 September 2024 Assessment period ends 15 November 2024 Semester 2 contact information
Time commitment details
160 hours - approaximately 3 hrs (preperation, research and revision) for each contact hour.
What do these dates mean
Visit this webpage to find out about these key dates, including how they impact on:
- Your tuition fees, academic transcript and statements.
- And for Commonwealth Supported students, your:
- Student Learning Entitlement. This applies to all students enrolled in a Commonwealth Supported Place (CSP).
Subjects withdrawn after the census date (including up to the ‘last day to withdraw without fail’) count toward the Student Learning Entitlement.
Additional delivery details
This Dual-Delivery subject has On Campus assessment components.
Last updated: 8 November 2024
Further information
- Texts
- Available to Study Abroad and/or Study Exchange Students
Last updated: 8 November 2024